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MW 306.12 Da, Purity >98%. Potent, selective and cell-permeable Ca²+-dependent calpain inhibitor (Ki values are 210 and 370 nM for calpain-1 and calpain-2 respectively). Non-competitive and non-peptide. Irreversibly inhibits ICa through AMPA receptors. Anti-ischemic effects in vivo. .
GFAP VHH (SdAb2409 GFAP) is a recombinant Alpaca VHH antibody that recognizes single-domain rat GFAP Featuring Biotiums bright and photostable red fluorescent CF583R Dye this antibody conjugate has been validated in Immunofluorescence It is supplied at 200 uL at 0 1 mg/mL
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A 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM); shows weaker affinity for EP receptors, with Ki values of > 100 nM for EP1-3 and > 10 nM for EP4
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MW 585.7 Da, Purity >98%. Potent, selective HSP90 inhibitor (IC₅₀ = 5 nM). Anticancer activity, including cytostatic, proapoptotic and antiangiogenic properties in vitro and in vivo.
A DNA sequence encoding the Influenza A H1N1 (A/Missouri/11/2025) Neuraminidase / NA (XRI62650.1) (Ile30-Asn469) was fused with a polyhistidine tag at the C-terminus.
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MW 352.39 g/mol, Purity >98%. Selective, cell-permeable Hsp90 ATPase inhibitor (IC₅₀ values are 3.2 μM and 6.6 μM for Human Hsp90 beta and yeast Hsp90 respectively). Exhibits no detectable effects against Human Hsp72 ATPase or topoisomerase II. Shows antiproliferative effects. Upregulates Hsp72 and downregulates c-Raf and cdk4. Antitumor activity is independent of NQO1/DT-diaphorase and P-glycoprotein expression.